Optica Applicata 2017(Vol.47), No.2, pp. 225-231


Neurotransmitters detection using a fluorescence-based sensor with graphene quantum dots
Sylwia Baluta, Joanna Cabaj, Karol Malecha

Keywords
sensor, dopamine, fluorescence, Förster resonance energy transfer, quantum dots

Abstract
In the paper, the development and performance of an optical sensor for detection of neurotransmitters (dopamine) is presented. The concentration of dopamine is measured basing on fluorescence quenching of graphene quantum dots. In the sensor, the dopamine molecules coat the graphene quantum dots surface – in result, the quenching of fluorescence occurs due to the Förster resonance energy transfer. The changes in fluorescence correspond to specific concentrations of the neurotransmitter in tested samples, so it is possible to accurately determine the concentration of dopamine in the sample.


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